Ceflonac -SP
Aceclofenac, Paracetamol &
Serratiopept
idase Tablets

 

Composition:

Each film coated tablet contains:

Aceclofenac BP          100 mg

Paracetamol BP         500 mg

Serratiopeptidase        15 mg

(As enteric coated granules equivalent to
30,000 Serratiopeptidase Units)
Pharmacodynamic properties

Acedofenac is a non-steroidal agent with marked anti-inflammatory  and analgesic properties. The mode of action of aceclofenac is largely based on the inhibition  of  prostaglandin synthesis. Aceclofenac is a potent inhibitor of  the enzyme, cyc1o-oxygenase, which is involved in the production of prostaglandins.

Paracetamof is a non-opiate para-aminophenol derivative that 

exhibits analgesic  and antipyretic activity. It does not possess anti-
inflammatory activity.

Serratiopeptidase binds to 2-macroglobulin in the blood in a 1:1
ratio. This helps to mask its antigenicity but retains its enzymatic
activity.
Levels of serratiopeptidase and slowly transferred to the
exudates at the site of infection and ioflarnrnation and gradually
b
lood levels decline. 

 Indications:

Resolution of inflammation due to bone and soft tissue injury.
R
esolution ofpost-operative pain, lntlarnmauon and oedema.