COATAL® Artemether - Lumefantrine

Anti-Malarials

Each tablet/linked satchet/60ml bottle (24g) contains
                                                              Artemether                                lumenfantrine
Coatal family pack (tablet)                          20                                             120
Coatal Forte             (tablet)                        80                                             480
Coatal granules        (sachet)                       20                                             120
Coatal oral Suspension (bottle)                  180                                          1080
Pharmacology and indications:
Coatal is a combination of Artemether and Lumefantrine which acts as a blood schizonticide and is indicated for the treatment of Adults and children with acute uncomplicated infections due to both sensitive and multi drug - resistant strains of P. falciparum.
Dosage:
(Tablets)
Adults and children 14yrs and above:  4 tablets for a start and to be repeated after 8 hours and then 4 tablets to be taken 2 times daily for the next 2 days or 1 tablet of Coatal forte for a start and 1 tablet after 8 hours and then 1 tablet to be taken 2 times daily for the next 2 days.

Children (9 – 14 yrs): 3 tablets for a start and 3 tablets after 8 hours and then 3 tablets to be taken 2 times daily for the next 2 days.
Children (3 – 8 yrs) 2 tablets for a start, then 2 tablets after 8 hours and then 2 tablets to be taken 2 times daily for 2 days.
Children (0 – 3 yrs) 1 sachet for a start, then I sachet after 8 hours and then 1 sachet to be taken 2 times daily for the next 2 days.
(Oral suspension)


Body weight

Number of milliliters

 

1st day

2nd day

3rd day

5kg

7ml

7ml

7ml

7.5kg

10ml

10ml

10ml

10kg

14ml

14ml

14ml

15kg

20ml

20ml

20ml

Contraindications:
Coatal is contraindicated in patients with hypersensitivity to any of the active ingredients or any of the excipients.
Its consideration:  is also contraindicated in the first trimester of pregnancy.
Precautions for use:
Coatal is not recommended for prophylaxis. 
Nursing Coatal should be taken with high-fat food or drinks such as milk. Patients should be encouraged to resume normal eating as soon as food can be tolerated since this improves absorption of artemether and Lumefantrine. In the event of vomiting within 1 hour of administration, a repeat dose should be taken.
Drug interactions:
The likelihood of Coatal interacting with other drugs is minimal in view of its short duration of administration and wide therapeutic index.
Adverse effects:
Coatal is generally well tolerated by adults and children, however, adverse effects might include abdominal pain, diarrhoea, nausea, vomiting, headache and fatigue.